Letrozole Drug Description
What is Letrozole?
Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by reducing estrogen levels in the body. This reduction can help slow or stop the growth of certain types of breast tumors that require estrogen to grow.
Mechanism of Action
The letrozole drug description highlights its method of action:
- Inhibits the aromatase enzyme, preventing the conversion of androgens into estrogens.
- Results in lower circulating estrogen levels.
- Helps in shrinking existing tumors and may prevent the development of new ones.
Indications
Letrozole is indicated for:
- Adjuvant treatment of early-stage hormone receptor-positive breast cancer.
- Treatment of advanced breast cancer after tamoxifen therapy.
- Reduction of recurrence risk Letrozol Zentiva 2.5mg drug description in postmenopausal women with hormone receptor-positive breast cancer.
Dosing Information
The typical dosage of letrozole is:
- 2.5 mg taken orally once daily.
- Dosage may vary based on individual patient factors and doctor’s recommendations.
- It can be taken with or without food.
Side Effects
Common side effects associated with letrozole include:
- Hot flashes
- Joint pain or stiffness
- Fatigue
- Nausea
- Bone thinning (osteoporosis)
Serious Side Effects
While rare, letrozole can cause more serious side effects such as:
- Heart problems
- Liver dysfunction
- Severe allergic reactions
FAQs About Letrozole
1. How long should I take letrozole?
Typically, treatment duration is five years, but this may vary based on individual circumstances and doctor’s advice.
2. Can I take letrozole if I’m pregnant?
No, letrozole is contraindicated during pregnancy due to potential harm to the fetus. Always inform your healthcare provider if you are pregnant or plan to become pregnant.
3. Are there any dietary restrictions while taking letrozole?
There are no specific dietary restrictions; however, maintaining a healthy diet may help manage side effects.
4. What should I do if I miss a dose?
If a dose is missed, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Conclusion
The letrozole drug description provides crucial information about its role in managing breast cancer. It’s essential for patients to discuss potential benefits and risks with their healthcare providers to ensure an informed treatment decision.